Bluenesse® - Stress relief for cognitive performance

Bluenesse® is a patented lemon balm extract (Melissa officinalis), standardised to 6% rosmarinic acid. With a studied mechanism of action supporting cognitive function, Bluenesse® is associated with changes in cortisol levels observed within 1 hour in clinical studies, and helps support a normal stress response and cognitive performance. Supported by published clinical trials. 300mg/day.

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Bluenesse® - Key features

  • Patented, standardised lemon balm extract
  • Associated with measurable changes in cortisol levels within 1 hour
  • Supports a normal stress response
  • Contributes to emotional comfort without stimulant effects
  • Supports cognitive performance, including memory and alertness

Science supporting Bluenesse®

Bluenesse® has been studied for its effects on stress response and cognitive performance, with outcomes observed within 1 hour in two published acute human clinical studies. Its mechanism of action has been investigated through in‑vitro studies, including documented receptor‑binding properties.

Characterisation

Bluenesse® is a botanical extract obtained by water extraction of lemon balm leaves (Melissa officinalis L.), a traditional herb native to Europe. Specific batches of lemon balm are selected for their biological activity profile, assessed through standardised in‑vitro testing, ensuring consistency and quality of the extract.

Bluenesse® is standardised to 6% rosmarinic acid, its primary characterised bioactive compound.

Primary active compounds
      Rosmarinic acid                  ≥6%

Composition: Lemon balm water extract (Melissa officinalis L.)

Recommended daily dosage: 300 mg

Clinically supported benefits

Randomised, placebo-controlled, cross-over studies.

LOCATIONS Australia Australia
DURATION

Acute study
1 training day + 4 testing days

Acute study
1 training day + 4 testing days
POPULATIONS

25 subjects
17 women & 8 men
Age: 18-39 years old

21 subjects
8 women & 13 men
Age: 21-30 years old
PROTOCOLS

No caffeine, Light meal
Test at 12pm or 4pm to reduce cortisol level variability
3 blocs of tests: Pre testing/ After 1 hour of Bluenesse intake/ After 3 hour of Bluenesse intake

Cortisol measurement
Anxiety evaluation
Cognitive performance

No caffeine, Light meal
Test at 12pm or 4pm to reduce cortisol level variability
3 blocs of tests: Pre testing/ After 1 hour of Bluenesse intake/ After 3 hour of Bluenesse intake

Cortisol measurement
Anxiety evaluation
Cognitive performance
INTAKES

ICED DRINK 480 ml/day
300 mg of Bluenesse + fruit sweeteners
Placebo + artificial sweeteners

YOGHURT 250 g/day
300 mg of Bluenesse + fruit sweeteners
Placebo + artificial sweeteners


Cortisol levels and anxiety.

 

Statistically significant changes in cortisol levels were observed following Bluenesse® consumption, compared with baseline and placebo conditions in acute settings.

Changes in stress response scores were observed, consistent with support of a normal stress response following intake.

Nootropic effect



Statistically significant changes were observed in cognitive performance parameters, including working memory, alertness, mathematical task performance and immediate word recall, at 1 hour and 3 hours post‑consumption, compared with placebo.

Certifications & Compliance

No allergens, non-GMO, Kosher, Halal, gluten-free, suitable for vegetarians

References

MECHANISTIC STUDIES
Buchwald-Werner S. et al. Agro Food Industry Hi Tech. 2015; vol 26 (1)

CLINICAL TRIALS
Scholey A. et al. Nutrients. 2014; 6, 4805-4821

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This website is intended to provide information about Biotexia’s ingredients, used in various food/dietary supplement products around the world. It is only intended for business to business and to provide information to food/dietary supplement professionals and is not designed for the general public. Statements used on this website have not been evaluated by competent authority. Products are not intended to diagnose, treat, cure or prevent any disease.